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← Index: IBPS & SBI Clerk General Awareness — Complete Guide 2026Chapter 21
Study Guide · Chapter 21

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Why This Chapter Matters

Of the three sciences banking exams sample from, biology contributes the most reliably repeated questions, typically 2 to 4 marks across IBPS Clerk, IBPS PO, and SBI Clerk General Awareness papers. The reason is simple: biology questions in this exam family lean heavily on the human body, common diseases, and vitamin deficiencies, topics that get recycled year after year because they are genuinely useful general knowledge, not because examiners lack imagination. If you master vitamin deficiency diseases and the basics of human body systems, you are covering the single most exam-productive corner of science GA in this entire exam family.

The biggest mistake aspirants make here is memorizing vitamin names and deficiency diseases as an unconnected list, then mixing them up under pressure, confusing which vitamin causes night blindness versus which one causes scurvy. A second frequent error is confusing similarly-named body parts or systems, like mistaking the pancreas for the liver, or confusing arteries and veins. This chapter builds every fact around a functional story, why the body needs this vitamin, what job this organ actually does, so that recall under exam stress becomes logical deduction rather than a coin flip between two half-remembered facts.

Human Body Systems: The Basics

The human body runs through several interconnected systems, each with a defined job, much like different departments in a well-run organization, each handling a distinct function but constantly communicating with the others to keep the whole operation running.

The Digestive System

Digestion begins the moment food enters your mouth, where saliva, containing the enzyme amylase, starts breaking down starches even before you swallow. Food then travels down the oesophagus into the stomach, where hydrochloric acid and the enzyme pepsin break down proteins into smaller fragments, churning food into a semi-liquid mixture.

From the stomach, partially digested food moves into the small intestine, the primary site of both digestion and nutrient absorption, and by far the longest section of the digestive tract at roughly 6-7 metres in an adult. Two major organs feed digestive juices into the small intestine here: the liver produces bile, stored in the gallbladder and released to break down fats into smaller droplets a process called emulsification, and the pancreas releases digestive enzymes that break down carbohydrates, proteins, and fats simultaneously.

Absorbed nutrients pass through the intestinal wall into the bloodstream, while undigested material moves into the large intestine, where water is reabsorbed and the remaining waste is compacted before elimination.

Exam trap: The liver and pancreas are frequently confused because both send secretions into the small intestine to aid digestion. Remember the liver produces bile (essential for fat digestion, stored separately in the gallbladder) while the pancreas produces digestive enzymes directly, and separately performs an entirely different job too: regulating blood sugar through insulin and glucagon. A question describing "the largest gland in the human body" wants the liver, while a question about "insulin-producing organ" wants the pancreas.

Memory hook: "The Kitchen Assembly Line." Picture your digestive system as a kitchen assembly line preparing a meal for delivery. The mouth is the chopping station (mechanical and initial enzymatic breakdown). The stomach is the pressure cooker (acid and churning). The liver is the sauce chef sending bile to help break down oily ingredients. The pancreas is the seasoning station adding enzymes for every food group at once. The small intestine is the packing counter where the finished, usable nutrients get boxed up and shipped into the bloodstream. The large intestine is the cleanup crew, recovering water and bagging the trash for disposal.

The Respiratory System

Breathing draws air through the nose or mouth, down the trachea (windpipe), which branches into two bronchi, one leading to each lung, and further divides into smaller bronchioles ending in tiny air sacs called alveoli. The alveoli are where actual gas exchange happens: oxygen from inhaled air passes into the surrounding blood capillaries, while carbon dioxide waste passes from the blood into the alveoli to be exhaled. An adult's lungs contain hundreds of millions of alveoli, giving them an enormous total surface area for gas exchange, roughly the size of a badminton court when spread flat, packed into a space that fits inside your chest.

The diaphragm, a dome-shaped muscle beneath the lungs, drives the mechanics of breathing: it contracts and flattens to pull air into the lungs (inhalation) and relaxes back into its dome shape to push air out (exhalation).

The Circulatory System

The heart is a muscular pump with four chambers: two upper chambers called atria (singular: atrium) and two lower chambers called ventricles. Blood low in oxygen returns from the body into the right atrium, moves to the right ventricle, and gets pumped to the lungs to pick up oxygen. Oxygen-rich blood returns from the lungs into the left atrium, moves to the left ventricle, and gets pumped out to the entire body, the strongest chamber of the four since it must push blood the farthest.

Arteries carry blood away from the heart, typically oxygen-rich blood under high pressure (the major exception is the pulmonary artery, which carries oxygen-poor blood to the lungs). Veins carry blood back toward the heart, typically oxygen-poor blood under lower pressure (the major exception is the pulmonary vein, which carries oxygen-rich blood from the lungs back to the heart). Capillaries are the tiniest blood vessels, so thin-walled that oxygen, nutrients, and waste products can pass directly through them into and out of surrounding tissue.

Exam trap: A recurring point of confusion is assuming "arteries always carry oxygenated blood" and "veins always carry deoxygenated blood." This is true almost everywhere in the body, but the pulmonary circuit reverses it: the pulmonary artery carries oxygen-poor blood to the lungs, and the pulmonary vein carries oxygen-rich blood back from the lungs. The safest rule to remember is functional, not compositional: arteries carry blood away from the heart, veins carry blood toward the heart, regardless of oxygen content.

Blood itself has four main components. Red blood cells (RBCs), containing the protein haemoglobin, carry oxygen throughout the body and give blood its red color. White blood cells (WBCs) form the immune system's frontline defense against infection. Platelets enable blood clotting, sealing wounds and preventing excessive blood loss. Plasma, the liquid component, carries all these cells along with dissolved nutrients, hormones, and waste products.

Blood group classification, based on the ABO system combined with the Rh factor, is a frequent exam topic: humans have blood types A, B, AB, or O, each either Rh positive or Rh negative. O negative is often called the "universal donor" since it can typically be given to patients of any blood type in an emergency, while AB positive is often called the "universal recipient" since a person with this type can typically receive blood from any donor type.

The Nervous System

The brain and spinal cord together form the central nervous system (CNS), the body's command and control center. The brain itself divides into three major regions: the cerebrum, the largest part, responsible for conscious thought, voluntary movement, memory, and reasoning; the cerebellum, tucked below the cerebrum, responsible for balance and coordination of movement; and the medulla oblongata (part of the brainstem), responsible for involuntary, life-sustaining functions like heartbeat, breathing rate, and blood pressure regulation, functions your body performs constantly without you ever consciously thinking about them.

Nerve signals travel through specialized cells called neurons, which transmit electrical and chemical signals throughout the body at remarkable speed, allowing you to pull your hand back from a hot surface within a fraction of a second, a rapid, largely automatic response called a reflex action that bypasses full conscious processing in the brain to save critical reaction time.

The Skeletal and Muscular Systems

An adult human skeleton contains 206 bones, providing structural support, protecting vital organs (the ribcage shields the heart and lungs, the skull protects the brain), and working with muscles to enable movement. Interestingly, babies are born with roughly 270 individual bones, many of which naturally fuse together during growth into childhood and adolescence, explaining the drop to 206 by adulthood.

The longest bone in the human body is the femur (thigh bone), and the smallest bone is the stapes, a tiny bone inside the ear involved in transmitting sound vibrations. Cartilage, a flexible connective tissue found at joints, in the ears, and in the nose, is softer and more flexible than bone, cushioning joints and allowing smooth movement without bone directly grinding against bone.

Common Diseases and Vitamin Deficiencies

This is the single most exam-productive subtopic in banking GA biology, and it rewards a functional understanding far more than blind memorization.

Vitamins and Their Deficiency Diseases

Each vitamin performs a specific job in the body, and when that vitamin is missing from the diet for an extended period, the resulting deficiency disease directly reflects the job that vitamin was supposed to be doing. Learn the function, and the deficiency disease practically explains itself.

Vitamin A (retinol) supports vision, particularly in low light, and maintains healthy skin and mucous membranes. Its deficiency causes night blindness (difficulty seeing in dim light) and, in severe or prolonged cases, a condition called xerophthalmia (dryness and damage to the eye's surface). Rich sources include carrots, spinach, mangoes, and liver.

Vitamin B1 (thiamine) supports nerve function and carbohydrate metabolism, converting food into usable energy. Its deficiency causes beriberi, a disease affecting the nervous and cardiovascular systems, historically linked to populations relying heavily on polished (husk-removed) white rice as a dietary staple, since the thiamine-rich husk is removed during polishing.

Vitamin B3 (niacin) deficiency causes pellagra, classically remembered by its "three Ds": dermatitis (skin inflammation), diarrhoea, and dementia, historically common in populations relying heavily on maize (corn) as a dietary staple without adequate dietary variety.

Vitamin B12 (cobalamin) is essential for red blood cell formation and nerve function. Its deficiency causes a type of anaemia called pernicious anaemia, along with nerve-related symptoms. Since vitamin B12 occurs almost exclusively in animal-derived foods (meat, eggs, dairy, fish), strict vegetarians and vegans face a genuinely elevated risk of deficiency and are often medically advised to consider supplementation.

Vitamin C (ascorbic acid) supports collagen formation (essential for healthy skin, gums, and blood vessels), wound healing, and immune function. Its deficiency causes scurvy, historically infamous among sailors on long sea voyages who lacked access to fresh fruits and vegetables, causing bleeding gums, loose teeth, and slow-healing wounds. Citrus fruits, amla (Indian gooseberry, exceptionally rich in vitamin C), and guava are excellent sources.

Vitamin D (calciferol) regulates calcium and phosphorus absorption, essential for strong bones and teeth. Its deficiency causes rickets in children (soft, weakened, and often bowed bones) and osteomalacia in adults (bone softening and pain). Unusually among vitamins, the human body can manufacture vitamin D itself when skin is exposed to adequate sunlight, which is why it is often called the "sunshine vitamin."

Vitamin K is essential for normal blood clotting. Its deficiency causes excessive, difficult-to-control bleeding even from minor cuts and injuries, since the blood loses its ability to clot efficiently.

Exam trap: Night blindness (vitamin A) and scurvy (vitamin C) are the two most frequently tested deficiency diseases, and students under time pressure often swap them. Anchor the connection functionally: Vitamin A supports vision, so its absence blinds you in low light. Vitamin C supports connective tissue and gums, so its absence causes bleeding gums and scurvy. Never memorize the letter-disease pair alone; always attach the underlying function, since function-based memory survives exam stress far better than a bare list.

Memory hook: "A Bone-Blood-Skin-Sight Story Chain." Picture a single character walking through a story: first, this character cannot see well at night (that's vitamin A, for eyesight). They stumble and their gums start bleeding when they bump into something (vitamin C, for gums and healing). Their bones feel soft and bend under weight as they keep walking (vitamin D, for bones). Finally, a small scratch from the stumble refuses to stop bleeding (vitamin K, for clotting). One character, four symptoms in walking order, four vitamins, four deficiency diseases, linked into a single memorable mini-story instead of an isolated list.

Common Mineral Deficiencies

Beyond vitamins, mineral deficiencies also appear in exams. Iron deficiency causes anaemia, marked by fatigue and pale skin, since iron is essential for haemoglobin, the oxygen-carrying protein in red blood cells; without enough iron, the body cannot manufacture enough functional haemoglobin. Iodine deficiency causes goitre (an enlarged thyroid gland, visible as swelling in the neck) and, in severe cases during pregnancy or early childhood, impairs physical and mental development; this is exactly why iodized salt became a mandated public health intervention in India and many other countries. Calcium deficiency weakens bones and teeth over time and, alongside vitamin D deficiency, contributes to conditions like rickets in children and osteoporosis (fragile, porous bones) in older adults.

Diseases Caused by Microorganisms

Diseases caused by microorganisms fall into distinct categories, and knowing which pathogen type causes which disease is a common exam theme.

Bacterial diseases are caused by bacteria and are often treatable with antibiotics. Examples include tuberculosis (TB) (caused by Mycobacterium tuberculosis, primarily affecting the lungs), cholera (caused by Vibrio cholerae, a severe intestinal infection spread through contaminated water, causing extreme dehydration through watery diarrhoea), typhoid (caused by Salmonella typhi, also spread through contaminated food and water), and tetanus (caused by Clostridium tetani, entering the body through deep wounds and affecting the nervous system, causing severe muscle stiffness).

Viral diseases are caused by viruses, which cannot be treated with antibiotics (antibiotics work against bacteria specifically, not viruses) and instead usually require antiviral treatment, symptom management, or prevention through vaccination. Examples include influenza (flu), measles, chickenpox, polio (which can cause permanent paralysis, primarily in young children, and is the target of India's celebrated and largely successful pulse polio immunization campaign), hepatitis (several distinct viral types affecting the liver, labelled A through E), and dengue and chikungunya (both spread specifically by the Aedes mosquito, distinct from the Anopheles mosquito responsible for malaria).

Exam trap: Malaria and dengue are both mosquito-borne, but they are transmitted by two entirely different mosquito genera and caused by two entirely different types of pathogen. Malaria is caused by a parasite (Plasmodium, a single-celled protozoan, not a bacterium or virus) transmitted specifically by the female Anopheles mosquito. Dengue is caused by a virus transmitted specifically by the Aedes mosquito. This exact pairing, pathogen type and mosquito genus, is one of the most frequently tested disease-vector questions in banking and SSC GA papers alike.

Fungal diseases, caused by fungi, include common skin infections like ringworm and athlete's foot, generally less severe than bacterial or viral diseases but persistent and often recurring without proper treatment.

Disease Pathogen Type Causative Agent/Vector
Tuberculosis Bacteria Mycobacterium tuberculosis
Cholera Bacteria Vibrio cholerae (contaminated water)
Typhoid Bacteria Salmonella typhi (contaminated food/water)
Malaria Parasite (protozoan) Female Anopheles mosquito
Dengue Virus Aedes mosquito
Polio Virus Contaminated water/food, person-to-person
Chickenpox Virus Airborne/direct contact
Ringworm Fungus Skin contact

Plant Biology Basics

Plants form the base of nearly every food chain on Earth, and banking exams test a light, functional layer of plant biology, mostly centered on photosynthesis and basic plant structure.

Photosynthesis is the process by which green plants manufacture their own food, using sunlight energy to convert carbon dioxide (absorbed from air through tiny pores) and water (absorbed through roots) into glucose, releasing oxygen as a byproduct. This entire process depends on chlorophyll, the green pigment housed inside cell structures called chloroplasts, which absorbs sunlight energy and drives the chemical reaction; chlorophyll's green color comes precisely from the fact that it reflects green light while absorbing red and blue wavelengths for energy.

Think of a leaf as a tiny solar-powered food factory. Sunlight is the electricity bill paid for free by the sun. Carbon dioxide and water are the raw ingredients delivered daily, one through the air, one through the roots. Chlorophyll is the factory machinery that actually runs the conversion process. Glucose is the finished product, stored as food energy, and oxygen is the factory's waste exhaust, except in this one remarkable case, the "waste" happens to be the exact gas every animal on Earth needs to breathe.

A plant's basic structure divides into roots (anchor the plant, absorb water and dissolved minerals from soil), stem (provides structural support and transports water, minerals, and food between roots and leaves), and leaves (the primary site of photosynthesis, thanks to their broad, thin shape maximizing sunlight capture). Transport within a plant happens through two specialized tissue types: xylem, which carries water and dissolved minerals upward from roots to leaves, and phloem, which carries the glucose food produced in leaves downward and outward to every other part of the plant that needs energy, including the roots themselves.

Exam trap: Students frequently confuse xylem and phloem, since both are plant transport tissues running side by side. The cleanest way to separate them: xylem moves water upward (root to leaf, a one-way street), while phloem moves food in whichever direction it is needed (leaf outward to any growing or storing part of the plant, a two-way distribution network). If a question mentions "upward transport of water," it wants xylem; if it mentions "distribution of food/sugar," it wants phloem.

Transpiration is the process by which plants lose water vapor through tiny pores on their leaves called stomata, the same pores through which carbon dioxide enters and oxygen exits during photosynthesis. Transpiration creates a continuous pulling effect that helps draw water up through the xylem from the roots, similar to how sucking on a straw pulls liquid upward from the bottom of a glass.

Respiration, unlike photosynthesis, happens in plants continuously, day and night, just as it does in animals: plants also break down glucose using oxygen to release usable energy, producing carbon dioxide and water as byproducts, essentially running the reverse chemical process of photosynthesis. The key exam-relevant distinction is that photosynthesis only happens in the presence of sunlight and only in cells containing chlorophyll, while respiration happens constantly, in every living plant cell, with or without light.

Plant reproduction happens through two broad routes. Sexual reproduction involves pollination, the transfer of pollen from a flower's male part (stamen) to the female part (pistil), which can happen through wind, water, insects, or birds, and leads to fertilization and seed formation. Asexual reproduction produces new plants without seeds or pollination, through methods like cuttings (a stem piece grown into a new plant), grafting (joining tissue from two different plants), or natural runners and tubers (like how a potato sprouts new plants from its eyes), commonly used in agriculture and horticulture to reliably reproduce a plant with exactly the desired characteristics of its parent.

Quick Revision — One-Line Facts

  • Saliva contains amylase, which begins starch digestion in the mouth.
  • The liver produces bile; the gallbladder stores it; both aid fat digestion.
  • The pancreas produces digestive enzymes and also regulates blood sugar via insulin and glucagon.
  • The small intestine is the primary site of nutrient absorption.
  • Gas exchange in the lungs happens in tiny air sacs called alveoli.
  • The diaphragm drives breathing by contracting (inhale) and relaxing (exhale).
  • The heart has four chambers: two atria (upper) and two ventricles (lower).
  • Arteries carry blood away from the heart; veins carry blood toward the heart, regardless of oxygen content.
  • Haemoglobin in red blood cells carries oxygen and gives blood its red color.
  • O negative blood is the universal donor; AB positive is the universal recipient.
  • The cerebrum governs conscious thought; the cerebellum governs balance and coordination.
  • An adult human skeleton has 206 bones; the femur is the longest, the stapes the smallest.
  • Vitamin A deficiency causes night blindness; sources include carrots and spinach.
  • Vitamin B1 deficiency causes beriberi, linked to polished rice diets.
  • Vitamin B3 deficiency causes pellagra ("three Ds": dermatitis, diarrhoea, dementia).
  • Vitamin B12 deficiency causes pernicious anaemia; found mainly in animal-based foods.
  • Vitamin C deficiency causes scurvy; rich sources include citrus fruits and amla.
  • Vitamin D deficiency causes rickets (children) and osteomalacia (adults); made by skin using sunlight.
  • Vitamin K deficiency impairs blood clotting.
  • Iron deficiency causes anaemia; iodine deficiency causes goitre.
  • Iodized salt is a public-health measure to prevent iodine deficiency.
  • Malaria is caused by a Plasmodium parasite, spread by the female Anopheles mosquito.
  • Dengue is caused by a virus, spread by the Aedes mosquito.
  • Antibiotics treat bacterial infections, not viral ones.
  • Polio is a viral disease targeted by India's pulse polio immunization campaign.
  • Chlorophyll in chloroplasts absorbs sunlight to drive photosynthesis.
  • Xylem carries water upward from roots to leaves; phloem distributes food throughout the plant.
  • Stomata are the tiny leaf pores through which gases and water vapor pass.
  • Photosynthesis needs light and chlorophyll; respiration happens continuously in all living plant cells.
  • Pollination transfers pollen from the stamen to the pistil, enabling sexual reproduction in flowering plants.

Memory Tables

Vitamin Deficiency Quick Reference

Vitamin Common Name Deficiency Disease Good Source
Vitamin A Retinol Night blindness / xerophthalmia Carrots, spinach, liver
Vitamin B1 Thiamine Beriberi Whole grains, legumes
Vitamin B3 Niacin Pellagra Meat, peanuts, whole grains
Vitamin B12 Cobalamin Pernicious anaemia Meat, eggs, dairy, fish
Vitamin C Ascorbic acid Scurvy Citrus fruits, amla, guava
Vitamin D Calciferol Rickets/osteomalacia Sunlight exposure, fortified milk
Vitamin K Phylloquinone Poor blood clotting Green leafy vegetables

Disease, Pathogen, and Transmission at a Glance

Disease Caused By Spread Through
Tuberculosis Bacteria Airborne droplets
Cholera Bacteria Contaminated water
Typhoid Bacteria Contaminated food/water
Malaria Parasite Female Anopheles mosquito
Dengue Virus Aedes mosquito
Chickenpox Virus Direct/airborne contact
Ringworm Fungus Skin contact

Practice MCQs

Q1. Which organ produces bile to aid in the digestion of fats? (a) Pancreas (b) Liver (c) Kidney (d) Stomach

Q2. Where does the actual exchange of oxygen and carbon dioxide take place in human lungs? (a) Trachea (b) Bronchi (c) Alveoli (d) Diaphragm

Q3. Which blood vessels always carry blood toward the heart, regardless of oxygen content? (a) Arteries (b) Veins (c) Capillaries (d) Aorta only

Q4. Deficiency of which vitamin causes night blindness? (a) Vitamin B12 (b) Vitamin C (c) Vitamin A (d) Vitamin D

Q5. Beriberi, a disease linked to diets heavy in polished rice, is caused by deficiency of: (a) Vitamin C (b) Vitamin B1 (thiamine) (c) Vitamin D (d) Vitamin K

Q6. Which vitamin deficiency causes scurvy, marked by bleeding gums and slow wound healing? (a) Vitamin A (b) Vitamin B12 (c) Vitamin C (d) Vitamin K

Q7. Malaria is caused by which type of organism? (a) Virus (b) Bacteria (c) Parasite (protozoan) (d) Fungus

Q8. Which mosquito genus transmits dengue? (a) Anopheles (b) Aedes (c) Culex (d) Mansonia

Q9. Iodine deficiency in the diet most directly leads to which condition? (a) Anaemia (b) Goitre (c) Rickets (d) Scurvy

Q10. Which part of the human brain primarily controls balance and coordination of movement? (a) Cerebrum (b) Cerebellum (c) Medulla oblongata (d) Spinal cord

Q11. The green pigment responsible for absorbing sunlight during photosynthesis is: (a) Haemoglobin (b) Chlorophyll (c) Melanin (d) Carotene

Q12. Which plant tissue transports water and dissolved minerals upward from roots to leaves? (a) Phloem (b) Xylem (c) Stomata (d) Cuticle

Q13. Which blood group is generally referred to as the "universal donor"? (a) AB positive (b) A negative (c) O negative (d) B positive

Q14. Antibiotics are effective in treating diseases caused by: (a) Viruses (b) Bacteria (c) Both viruses and bacteria equally (d) Fungi only

Q15. The total number of bones in an average adult human skeleton is: (a) 186 (b) 206 (c) 270 (d) 300

Answer Key

Q Answer Reason
1 (b) Liver The liver produces bile, which is stored in the gallbladder and released to emulsify and break down fats for digestion.
2 (c) Alveoli Alveoli are the tiny, thin-walled air sacs in the lungs where oxygen and carbon dioxide actually cross between air and blood.
3 (b) Veins Veins are functionally defined as vessels carrying blood toward the heart, regardless of oxygen content, unlike arteries, which carry blood away.
4 (c) Vitamin A Vitamin A directly supports vision in low light, so its deficiency causes night blindness and, if prolonged, xerophthalmia.
5 (b) Vitamin B1 (thiamine) Thiamine deficiency causes beriberi, historically linked to diets relying on polished rice, which strips away the thiamine-rich husk.
6 (c) Vitamin C Vitamin C is essential for collagen formation and wound healing; its absence weakens gums and blood vessels, causing scurvy.
7 (c) Parasite (protozoan) Malaria is caused by the Plasmodium parasite, a single-celled protozoan, not a bacterium or virus, transmitted by the female Anopheles mosquito.
8 (b) Aedes Dengue and chikungunya are both spread by the Aedes mosquito, distinct from the Anopheles mosquito that spreads malaria.
9 (b) Goitre Iodine deficiency impairs thyroid hormone production, causing the thyroid gland to enlarge visibly in the neck, a condition called goitre.
10 (b) Cerebellum The cerebellum specifically governs balance, posture, and coordinated movement, distinct from the cerebrum's role in conscious thought.
11 (b) Chlorophyll Chlorophyll, housed in chloroplasts, absorbs sunlight energy and drives the chemical reactions of photosynthesis.
12 (b) Xylem Xylem tissue moves water and dissolved minerals in one direction, upward from the roots to the leaves, unlike phloem's two-way food distribution.
13 (c) O negative O negative blood lacks the A, B, and Rh antigens that trigger immune rejection, making it broadly compatible as an emergency universal donor type.
14 (b) Bacteria Antibiotics specifically target bacterial cell structures and processes; they have no effect on viruses, which require antiviral treatment or vaccination instead.
15 (b) 206 An adult human skeleton contains 206 bones, down from roughly 270 at birth, since many bones naturally fuse together during growth.
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